Lissandra vs Anivia — Mid Lane Matchup Guide

How to win lane as Lissandra against Anivia · 52.21% win rate over 1,471 Emerald+ games · Updated 2026-07-27

Verdict: Lissandra is favoured — Lissandra owns 5 of the 7 game windows to Anivia's 2. Lissandra wins 52.21% of games vs Anivia in mid lane (1,471 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1LissandraLevel 1 favors you as a mobile threat against an immobile Anivia.
Level 2LissandraLevel 2 stays yours with your engage outpacing her setup.
Level 3LissandraLevel 3 your all-in punishes her mana-starved early game.
Levels 4-5LissandraLevels 4-5 you keep kill pressure through her egg and stun.
Level 6LissandraAt 6 your R lets you commit past her defensive tools.
First itemAniviaOn first item her Rod of Ages and Wall flip the zoning war to her.
Two+ itemsAniviaWith two items Anivia's range and scaling out-zone your engage entirely.

Early game (levels 1–5)

Levels 1-6 favor you: Anivia is a slow, mana-hungry sitting target, and your E-Q-W all-in punishes her before she has the mana or items to fight back, so look to bully her off CS and set up your jungler.

Read the rest of this matchup

The full Lissandra vs Anivia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Anivia vs Lissandra guide →
All Lissandra mid lane matchups →