How to win lane as Kassadin against Syndra · 51.03% win rate over 2,273 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Syndra | Syndra's longer-range poke edges out your early trades at level 1 |
| Level 2 | Syndra | She continues to out-poke you comfortably at level 2 |
| Level 3 | Syndra | Her sphere-stun combo threat keeps the lane hers through level 3 |
| Levels 4-5 | Syndra | Levels 4-5 stay in her favour as her combo damage scales ahead of yours |
| Level 6 | Syndra | Her level 6 Unleashed Power is her single biggest kill threat in the whole matchup |
| First item | Kassadin | Her first item extends that damage lead through your own early game |
| Two+ items | Kassadin | With Riftwalk stacks and a well-timed silence you finally flip the late-game duel back to you |
Levels 1-2 already favour Syndra's longer range poke, but it's not overwhelming yet — trade carefully, respect her spheres, and don't feed her easy Scatter the Weak stuns.
The full Kassadin vs Syndra report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Syndra vs Kassadin guide →
All Kassadin mid lane matchups →