Kassadin vs Annie — Mid Lane Matchup Guide

How to win lane as Kassadin against Annie · 55.04% win rate over 565 Emerald+ games · Updated 2026-07-27

Verdict: Winnable despite the lane — Annie owns 5 of the 7 game windows to Kassadin's 2, yet the win rate favours Kassadin: survive their windows and the game is yours. Kassadin wins 55.04% of games vs Annie in mid lane (565 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1AnnieHer poke and stun threat outclass your early kit with no items
Level 2AnnieStacked stun keeps punishing your approach through level 4
Level 3AnnieStill her lane heading into 6, since she outdamages your unitemized kit
Levels 4-5AnnieTibbers adds a burst/stun combo you can't survive without items
Level 6AnnieStill dangerous through this stage as her combo one-shots low-item targets
First itemKassadinFirst item sustain and damage let you start contesting trades evenly
Two+ itemsKassadinRiftwalk mobility lets you dodge her stun and burst her down first

Early game (levels 1–5)

Levels 1-2 already favor Annie because her Disintegrate poke is free damage on your farm attempts and her stun threat means you can't contest trades without risking a burst combo.

Read the rest of this matchup

The full Kassadin vs Annie report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Annie vs Kassadin guide →
All Kassadin mid lane matchups →