How to win lane as Seraphine against Kai'Sa · 52.67% win rate (22,058 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
Her DPS needs fights your charm postpones — poke the notes, sustain the chip, and encore the all-in backward.
Track: Kai'Sa's E — Supercharge (16–10s cooldown). Her reposition + stealth window — engage in the sixteen seconds after she burns it.
Read from Seraphine's seat: which stage windows this plan plays for against Kai'Sa.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Seraphine | Kai'Sa's short early range loses to your level-1 poke. |
| Level 2 | Seraphine | At level 2 your Q/E poke keeps her off the wave and behind. |
| Level 3 | Seraphine | Level 3 lets you slow-and-trade her fragile early kit. |
| Levels 4-5 | Seraphine | Through level 4-5 your poke still delays her evolves and farm. |
| Level 6 | Even / skill | Level 6 is even -- her R dive is countered by your Encore interrupt. |
| First item | Kai'Sa | Her first-item evolves spike her range and burst over you. |
| Two+ items | Kai'Sa | Late game her mobility and plasma burst hard-outscale your damage. |
You control levels 1-4: Kai'Sa is short-ranged and fragile before her evolves, so your Q poke and E slows chunk her at every last-hit and delay her scaling, while any support all-in favors you before her R comes online. She is fragile before her evolves, so poke her at every last-hit and slow her scaling rather than looking for a kill. Notes build off the wave while you do it. Beat Drop into a support engage is the punish, and the shield keeps whoever commits alive through her plasma burst.
Pooled Emerald+ win rates from Seraphine's side, sampled July 2026.
The full Seraphine vs Kai'Sa report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Seraphine, slightly — a 52.67% win rate edge over 22,058 games; execution can flip it.
Mostly — Seraphine has a small statistical edge (52.67% win rate), but execution decides this lane far more than the pick does.
Not a hard counter — Seraphine has a slight edge (52.67% win rate), and play quality decides the rest.
Seraphine takes Summon Aery on the Sorcery tree with Manaflow Band, Transcendence and Scorch, and Inspiration secondary (Biscuit Delivery and Cosmic Insight) vs Kai'Sa.
Start Doran's Ring + 2 Health Potions and back for Lost Chapter (≈1300g). Build Luden's / Moonstone by build first, then Rylai's, with Sorcerer's Shoes.
Playing the other side? Kai'Sa vs Seraphine guide →
All Seraphine bot lane matchups →
More Seraphine bot lane matchups: vs Heimerdinger · vs Jhin · vs Jinx · vs Kalista · vs Karthus · vs Kog'Maw