How to win lane as Seraphine against Kai'Sa · 56.02% win rate over 4,570 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Seraphine | Kai'Sa's short early range loses to your level-1 poke. |
| Level 2 | Seraphine | At level 2 your Q/E poke keeps her off the wave and behind. |
| Level 3 | Seraphine | Level 3 lets you slow-and-trade her fragile early kit. |
| Levels 4-5 | Seraphine | Through level 4-5 your poke still delays her evolves and farm. |
| Level 6 | Even / skill | Level 6 is even -- her R dive is countered by your Encore interrupt. |
| First item | Kai'Sa | Her first-item evolves spike her range and burst over you. |
| Two+ items | Kai'Sa | Late game her mobility and plasma burst hard-outscale your damage. |
You control levels 1-4: Kai'Sa is short-ranged and fragile before her evolves, so your Q poke and E slows chunk her at every last-hit and delay her scaling, while any support all-in favors you before her R comes online.
The full Seraphine vs Kai'Sa report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Kai'Sa vs Seraphine guide →
All Seraphine bot lane (adc) matchups →