Vladimir vs Vayne — Top Lane Matchup Guide

How to win lane as Vladimir against Vayne · 54.38% win rate (1,234 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: Vladimir is slightly favoured — 54.38% win rate over 1,234 games, and Vladimir's game plan below claims 5 of the 7 stage windows.

At a glance

Pool the condemn, Q-sustain through her poke, and out-scale her squishy kit once your AP comes online.

Track: Vayne's E — Condemn (20–12s cooldown). Wall-stun. Don’t get pinned.

Do

Q-poke her early
W-pool her burst
Out-scale her

Don't

Get kited and condemned
Fight her at 2 items
Pool too early

Runes & build vs Vayne

Start: Doran's Ring + 2 Health Potions
First back: Core component + boots (≈1300g)
First item: Riftmaker (drain scaling)
Then: Zhonya's Hourglass
Boots: Sorcerer's Shoes
Runes: Phase Rush (Sorcery): Manaflow Band, Transcendence, Scorch · Inspiration: Biscuit Delivery, Cosmic Insight · Shards: Adaptive Force, Adaptive Force, Health

Favour timeline — the windows in Vladimir's game plan

Read from Vladimir's seat: which stage windows this plan plays for against Vayne.

Stage	Favoured	Why
Level 1	Vladimir	Vayne must enter your E-Q range to farm, so you control the level-1 poke.
Level 2	Even / skill	Her level-2 Q Tumble trades are real, making the exchange skill-dependent.
Level 3	Even / skill	Level 3 stays skill-based as she can tumble-auto and reposition out of your Q.
Levels 4-5	Vladimir	By levels 4-5 your poke and healing clearly outpace her sustainless trades.
Level 6	Vladimir	Hemoplague plus your burst can kill her outright at level 6.
First item	Vladimir	Your first AP item hard-outdamages her early tumble pattern.
Two+ items	Vladimir	In a lane trade your scaling burst beats her before Final Hour ramps.

How to beat Vayne as Vladimir: the early game

You have the upper hand at level 1 — Vayne has to come into your E-Q range to farm, and her early trades hurt but leave her low without sustain. Poke her with Q Transfusion and E Tides of Blood whenever she steps up. The level 2-3 window is skill-based since her Q Tumble auto-reset trades are real, but if you respect Condemn you come out ahead. Don't get pinned to a wall by her E.

Hardest and easiest matchups for Vladimir in top lane

Pooled Emerald+ win rates from Vladimir's side, sampled July 2026.

Hardest

Vladimir vs Illaoi — 44.83% win rate
Vladimir vs Quinn — 45.31% win rate
Vladimir vs Gwen — 45.37% win rate

Easiest

Vladimir vs Mel — 59.35% win rate
Vladimir vs Swain — 56.82% win rate
Vladimir vs Zac — 55.19% win rate

Read the rest of this matchup

The full Vladimir vs Vayne report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Vladimir vs Vayne in top lane?

Vladimir, slightly — a 54.38% win rate edge over 1,234 games; execution can flip it.

Is Vladimir vs Vayne a skill matchup?

Mostly — Vladimir has a small statistical edge (54.38% win rate), but execution decides this lane far more than the pick does.

Does Vladimir counter Vayne?

Not a hard counter — Vladimir has a slight edge (54.38% win rate), and play quality decides the rest.

What runes does Vladimir take vs Vayne?

Vladimir takes Phase Rush on the Sorcery tree with Manaflow Band, Transcendence and Scorch, and Inspiration secondary (Biscuit Delivery and Cosmic Insight) vs Vayne.

What should Vladimir build vs Vayne?

Start Doran's Ring + 2 Health Potions and back for Core component + boots (≈1300g). Build Riftmaker (drain scaling) first, then Zhonya's Hourglass, with Sorcerer's Shoes.

More Vladimir top lane matchups: vs Trundle · vs Tryndamere · vs Urgot · vs Volibear · vs Warwick · vs Wukong