How to win lane as Vladimir against Cassiopeia · 52.66% win rate over 319 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Level 1 is even before Cassiopeia unlocks her Miasma zone. |
| Level 2 | Cassiopeia | At level 2 Twin Fang poke and poison sustain win her the trades. |
| Level 3 | Cassiopeia | Level 3 stays hers as Miasma zones your range and heals her. |
| Levels 4-5 | Cassiopeia | Levels 4-5 remain hers — poisoned, you lose the Twin Fang DPS race. |
| Level 6 | Even / skill | Level 6 is even as your first item arrives and you can dodge her stun. |
| First item | Vladimir | By your first item Crimson Pact haste out-ticks her Twin Fang sustain. |
| Two+ items | Vladimir | With 2+ items Hemoplague and burst delete her squishy frame. |
Level 1 is even before Cassiopeia has Miasma; trade Transfusion for her Q and neither commits. Don't step on poison ground and keep your distance.
The full Vladimir vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Cassiopeia vs Vladimir guide →
All Vladimir top lane matchups →
Also played in: Mid Lane