Vladimir vs Cassiopeia — Top Lane Matchup Guide

How to win lane as Vladimir against Cassiopeia · 52.66% win rate (319 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: Vladimir is slightly favoured — 52.66% win rate over 319 games, and Vladimir's game plan below claims 4 of the 7 stage windows.

At a glance

Weather the poke — drain her down and pool the Miasma answer.

Track: Cassiopeia's W — Miasma (24–16s cooldown). Grounds you — dashes and movement abilities are disabled inside it.

Do

  • Q-drain on cooldown
  • Pool her Miasma
  • E-charge behind the wave

Don't

  • Pool for poke
  • Fight before item spikes
  • Waste empowered Q on minions

Runes & build vs Cassiopeia

Start
Doran's Ring + 2 Health Potions
First back
Core component + boots (≈1300g)
First item
Riftmaker (drain scaling)
Then
Zhonya's Hourglass
Boots
Mercury's Treads
Runes
Phase Rush (Sorcery): Manaflow Band, Transcendence, Scorch · Inspiration: Biscuit Delivery, Cosmic Insight · Shards: Adaptive Force, Adaptive Force, Magic Resist

Favour timeline — the windows in Vladimir's game plan

Read from Vladimir's seat: which stage windows this plan plays for against Cassiopeia.

StageFavouredWhy
Level 1Even / skillLevel 1 is even before Cassiopeia unlocks her Miasma zone.
Level 2Even / skillAt level 2 Twin Fang poke and poison sustain win her the trades.
Level 3VladimirLevel 3 stays hers as Miasma grounds you and Twin Fang heals her.
Levels 4-5VladimirLevels 4-5 remain hers — poisoned, you lose the Twin Fang DPS race.
Level 6Even / skillLevel 6 is even as your first item arrives and you can dodge her stun.
First itemVladimirBy your first item Crimson Pact haste out-ticks her Twin Fang sustain.
Two+ itemsVladimirWith 2+ items Hemoplague and burst delete her squishy frame.

How to beat Cassiopeia as Vladimir: the early game

Level 1 is even before Cassiopeia has Miasma; Noxious Blast is 850 range to your 600, so trade only once she has stepped up, and never stand in poison.

Hardest and easiest matchups for Vladimir in top lane

Pooled Emerald+ win rates from Vladimir's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Vladimir vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Vladimir vs Cassiopeia in top lane?

Vladimir, slightly — a 52.66% win rate edge over 319 games; execution can flip it.

Is Vladimir vs Cassiopeia a skill matchup?

Mostly — Vladimir has a small statistical edge (52.66% win rate), but execution decides this lane far more than the pick does.

Does Vladimir counter Cassiopeia?

Not a hard counter — Vladimir has a slight edge (52.66% win rate), and play quality decides the rest.

What runes does Vladimir take vs Cassiopeia?

Vladimir takes Phase Rush on the Sorcery tree with Manaflow Band, Transcendence and Scorch, and Inspiration secondary (Biscuit Delivery and Cosmic Insight) vs Cassiopeia.

What should Vladimir build vs Cassiopeia?

Start Doran's Ring + 2 Health Potions and back for Core component + boots (≈1300g). Build Riftmaker (drain scaling) first, then Zhonya's Hourglass, with Mercury's Treads.

Related guides

Playing the other side? Cassiopeia vs Vladimir guide →
All Vladimir top lane matchups →

More Vladimir top lane matchups: vs Ambessa · vs Aurora · vs Camille · vs Cho'Gath · vs Darius · vs Dr. Mundo

Also played in: Mid Lane