How to win lane as Vladimir against Cassiopeia · 56.28% win rate over 1,107 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Cassiopeia | Cassiopeia's Q poison and grounded zone stop your walk-ups at level 1. |
| Level 2 | Cassiopeia | At level 2 her Twin Fang chains off poison to ramp damage you can't answer. |
| Level 3 | Cassiopeia | Level 3 her passive movespeed kites your Q and she owns the range war. |
| Levels 4-5 | Vladimir | By level 4 your Q sustain heals the chip and lets you contest the wave. |
| Level 6 | Cassiopeia | At 6 her Petrifying Gaze plus E spam out-trades your Hemoplague all-in. |
| First item | Cassiopeia | First-item Malignance makes her E endless and burns through your heal. |
| Two+ items | Vladimir | Two items in your sustain and amp finally facetank her poison and kill her. |
Cassiopeia dominates the early range war: her Q poison plus grounded zone stops you from walking up, and her Twin Fang E chains off the poison to ramp damage while you can't retaliate. Levels 1-3 her passive movespeed lets her float around your Q attempts and poke you down every time you step for CS. Don't try to trade, you'll just feed her E stacks and the grounding shuts off any pool escape from a gank. Sit behind minions, take the safe farm, and wait for your sustain to come online.
The full Vladimir vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Cassiopeia vs Vladimir guide →
All Vladimir mid lane matchups →
Also played in: Top Lane