How to win lane as Vladimir against Cassiopeia · 53.45% win rate (2,161 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
She pokes a champion whose poke heals — survive the early tax bracket and the sustain math forecloses on her.
Track: Cassiopeia's W — Miasma (24–16s cooldown). Grounds you — dashes and leaps are disabled inside it.
Read from Vladimir's seat: which stage windows this plan plays for against Cassiopeia.
This is Vladimir's own plan; across 2,161 pooled games the lane is leaning Vladimir.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Cassiopeia | Cassiopeia's Q poison and grounded zone stop your walk-ups at level 1. |
| Level 2 | Cassiopeia | At level 2 her Twin Fang chains off poison to ramp damage you can't answer. |
| Level 3 | Even / skill | Level 3 her passive movespeed kites your Q and she owns the range war. |
| Levels 4-5 | Even / skill | By level 4 your Q sustain heals the chip and lets you contest the wave. |
| Level 6 | Even / skill | At 6 her Petrifying Gaze plus E spam out-trades your Hemoplague all-in. |
| First item | Even / skill | First-item Malignance makes her E endless and burns through your heal. |
| Two+ items | Even / skill | Two items in your sustain and amp finally facetank her poison and kill her. |
Cassiopeia dominates the early range war: her Q poison plus grounded zone stops you from walking up, and her Twin Fang E chains off the poison to ramp damage while you can't retaliate. Levels 1-3 her passive movespeed lets her float around your Q attempts and poke you down every time you step for CS. Don't try to trade, you'll just feed her E stacks and the grounding shuts off any pool escape from a gank. Sit behind minions, take the safe farm, and wait for your sustain to come online.
Pooled Emerald+ win rates from Vladimir's side, sampled July 2026.
The full Vladimir vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Vladimir, slightly — a 53.45% win rate edge over 2,161 games; execution can flip it.
Mostly — Vladimir has a small statistical edge (53.45% win rate), but execution decides this lane far more than the pick does.
Not a hard counter — Vladimir has a slight edge (53.45% win rate), and play quality decides the rest.
Vladimir takes Phase Rush on the Sorcery tree with Nimbus Cloak, Transcendence and Scorch, and Resolve secondary (Bone Plating and Overgrowth) vs Cassiopeia.
Start Doran's Shield + Health Potion and back for Oblivion Orb (≈800g) — cuts her sustain. Build Riftmaker first, then Cosmic Drive, with Mercury's Treads / Sorcerer's Shoes.
Playing the other side? Cassiopeia vs Vladimir guide →
All Vladimir mid lane matchups →
More Vladimir mid lane matchups: vs Aurora · vs Azir · vs Brand · vs Diana · vs Ekko · vs Fizz
Also played in: Top Lane