How to win lane as Illaoi against Vayne · 53.76% win rate over 1,395 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Vayne | Vayne's Silver Bolts true damage and Tumble spacing win L1 harass. |
| Level 2 | Illaoi | At L2 your E-tether starts gluing a melee-range Vayne for a trade. |
| Level 3 | Illaoi | At L3 a tethered Vayne can't escape your W-into-tentacle burst. |
| Levels 4-5 | Illaoi | Levels 4-5 stay yours as she has no answer to E once locked. |
| Level 6 | Illaoi | Leap of Faith on a tethered Vayne is a guaranteed kill at 6. |
| First item | Illaoi | With your first item you still win any fight that starts on your E. |
| Two+ items | Vayne | Late game her item spikes let her kite and shred, flipping it to Vayne. |
Vayne edges L1 with Silver Bolts (W) %HP true damage chipping you as you walk up, and Tumble (Q) spacing your early Q pokes. Respect her auto harass and wait for your spike.
The full Illaoi vs Vayne report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Vayne vs Illaoi guide →
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