How to win lane as Senna against Nautilus · 52.44% win rate over 11,323 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Level 1 is even as his hook is dodgeable behind minions and you out-auto him otherwise. |
| Level 2 | Even / skill | Level 2 is a skill trade around his Q hook cooldown. |
| Level 3 | Even / skill | Level 3 stays even as you punish whiffed hooks and he threatens landed ones. |
| Levels 4-5 | Even / skill | Levels 4-5 are even as neither of you can force a clean kill yet. |
| Level 6 | Nautilus | Nautilus wins level 6 because R guarantees an unstoppable lockup chain you can't outrange. |
| First item | Nautilus | Nautilus keeps first item as hook range plus tank stats convert any Q into a kill. |
| Two+ items | Nautilus | Nautilus wins 2+ items because his homing R and tankiness beat your poke, forcing you to only peel. |
Levels 1-4 are a skill matchup decided by his Q: stand behind minions so his Dredge Line catches a creep, and when it whiffs, E-auto and Q-poke him during the cooldown to stay even.
The full Senna vs Nautilus report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Nautilus vs Senna guide →
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