Zed vs Lissandra — Mid Lane Matchup Guide

How to win lane as Zed against Lissandra · 50.31% win rate over 6,305 Emerald+ games · Updated 2026-07-27

Verdict: Zed is favoured — Zed owns 7 of the 7 game windows. Zed wins 50.31% of games vs Lissandra in mid lane (6,305 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1ZedZed favoured L1: her only poke is a dodgeable Q and she has no sustain to contest you.
Level 2ZedZed favoured L2: W-shadow Q chunks her freely whenever her E claw is down.
Level 3ZedZed favoured L3: you out-trade and deny CS with little counterplay from her.
Levels 4-5ZedZed favoured L4-5: perma-shove and roam pressure keep her off her scaling curve.
Level 6ZedZed favoured L6: Death Mark threatens the kill and forces out her defensive Frozen Tomb.
First itemZedZed favoured 1st item: lethality deletes her before her item-based durability comes online.
Two+ itemsZedZed favoured 2+ items: you keep the mid-game pick edge even as she scales into a tankier diver.

Early game (levels 1–5)

L1-2 is yours. Lissandra's only poke is a sidesteppable Q and she has no sustain, so shove her in and chunk her with W-shadow Q every time her E claw is down. Hold your dash to dodge her E-engage, and deny her CS to keep her off her scaling curve.

Read the rest of this matchup

The full Zed vs Lissandra report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Lissandra vs Zed guide →
All Zed mid lane matchups →