Lissandra vs Zed — Mid Lane Matchup Guide

How to win lane as Lissandra against Zed · 53.02% win rate over 6,281 Emerald+ games · Updated 2026-07-27

Verdict: Lissandra is favoured — Lissandra owns 3 of the 7 game windows. Lissandra wins 53.02% of games vs Zed in mid lane (6,281 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillLevel 1 is even as both of you just set up the wave with no kill pressure.
Level 2Even / skillLevel 2 stays a skill check as Zed's poke trades against your W block and E interrupt.
Level 3Even / skillLevel 3 is even with Zed's first all-in window balanced by your defensive cooldowns.
Levels 4-5Even / skillLevels 4-5 remain skill-dependent as the pre-6 poke war comes down to dodging and energy management.
Level 6LissandraAt level 6 you pull ahead because your R directly counters his death-mark all-in.
First itemLissandraAt first item Zhonya's plus your R lets you blank his entire commit and win the fights he starts.
Two+ itemsLissandraWith two-plus items you out-scale him as his single-target burst fades against your teamfight ult and peel.

Early game (levels 1–5)

Levels 1-5 are a genuine skill matchup. Zed wants to poke with Q and shove you in with W to set up roams, so track his energy and use W to block the key Q while keeping E up to punish any dash-in; if you play the wave even and dodge his poke, neither of you gets ahead.

Read the rest of this matchup

The full Lissandra vs Zed report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Zed vs Lissandra guide →
All Lissandra mid lane matchups →