Vladimir vs Twisted Fate — Mid Lane Matchup Guide

How to win lane as Vladimir against Twisted Fate · 52.41% win rate over 2,320 Emerald+ games · Updated 2026-07-27

Verdict: Vladimir is favoured — Vladimir owns 4 of the 7 game windows to Twisted Fate's 3. Vladimir wins 52.41% of games vs Twisted Fate in mid lane (2,320 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Twisted FateTF's level-1 Wild Cards and Blue Card poke out-range your melee Transfusion start.
Level 2Twisted FateAt level 2 his ranged poke keeps chipping you while you can't retaliate.
Level 3Twisted FateLevel 3 Pick a Card gank threat and Wild Cards pressure keep you on the back foot.
Levels 4-5VladimirLevels 4-5 your stacked Transfusion sustain out-heals his poke and you seize lane control.
Level 6VladimirAt 6 Hemoplague plus Sanguine Pool gives you an all-in and a Gold Card dodge he can't answer.
First itemVladimirOn first item your Rylai's/Riftmaker sustain fully negates his Wild Cards chip damage.
Two+ itemsVladimirWith 2+ items your teamfight amp and durability outscale a squishy roaming TF.

Early game (levels 1–5)

Twisted Fate controls the first three levels with Blue Card mana-efficient poke and Wild Cards wave pressure, and his Pick a Card stun makes early ganks lethal, so respect his range and farm safely without stepping into the minion wave.

Read the rest of this matchup

The full Vladimir vs Twisted Fate report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Playing the other side? Twisted Fate vs Vladimir guide →
All Vladimir mid lane matchups →