Syndra vs Vladimir — Mid Lane Matchup Guide

How to win lane as Syndra against Vladimir · 51.55% win rate over 4,464 Emerald+ games · Updated 2026-07-27

Verdict: Syndra is favoured — Syndra owns 7 of the 7 game windows. Syndra wins 51.55% of games vs Vladimir in mid lane (4,464 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1SyndraLevel 1 Syndra's Q pokes a sustain-less Vladimir who can barely trade back this early.
Level 2SyndraLevel 2 Syndra's added poke keeps Vlad low while his Q drain is still on a long cooldown.
Level 3SyndraLevel 3 the QE stun punishes Vlad hard whenever he steps up to farm.
Levels 4-5SyndraLevel 6 Syndra's R burst threatens Vlad; she just times it around his Sanguine Pool.
Level 6SyndraFirst-item Syndra out-damages Vlad before his drain-tank scaling and item spikes arrive.
First itemSyndraMid-game Syndra must convert her early lead, baiting the pool to burst Vlad before he outscales.
Two+ itemsSyndraFull build Vlad is tanky, so Syndra's edge is having ended the game on the lead she built early.

Early game (levels 1–5)

Syndra hard-punishes Vladimir's weak early game: he has no sustain items yet and his Q drain is on a long early cooldown, so Syndra's Q and QE poke keep him perpetually low. Vladimir wants to farm safely and survive to his item spikes, so Syndra should deny CS and zone him off the wave. Every bit of poke damage matters because Vlad only gets stronger with time.

Read the rest of this matchup

The full Syndra vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Vladimir vs Syndra guide →
All Syndra mid lane matchups →