How to win lane as Syndra against Karma · 52.9% win rate over 7,218 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Syndra | Level 1 favours you because Karma's base damage is weak and your Q pokes safely. |
| Level 2 | Syndra | Level 2 favours you as your QQ trade beats her Inner Flame when you dodge it. |
| Level 3 | Syndra | Level 3 favours you since E stun gives you an all-in she cannot answer. |
| Levels 4-5 | Syndra | Levels 4-5 favour you as your burst combo out-damages her shield-and-poke game. |
| Level 6 | Syndra | Level 6 favours you because your ult combo out-bursts a champ with no hard kill pressure. |
| First item | Syndra | First item favours you as your poke and combo outscale her utility kit in lane. |
| Two+ items | Syndra | At two-plus items you favour the matchup as a pick threat her shield can only delay. |
Levels 1-2 favour you: Karma's base damage is low and your Q Dark Sphere out-trades her Q Inner Flame when you dodge the empowered detonation.
The full Syndra vs Karma report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Karma vs Syndra guide →
All Syndra mid lane matchups →