How to win lane as Ryze against Cassiopeia · 49.62% win rate over 1,066 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Cassiopeia | Cassiopeia's Noxious Blast poke and fast wave push shove you under tower at level 1. |
| Level 2 | Even / skill | At level 2 you both trade spells evenly with no kill threat on either side. |
| Level 3 | Ryze | At level 3 you can Rune Prison and Overload-burst her before her Twin Fang fully ramps. |
| Levels 4-5 | Cassiopeia | Her Miasma slow at 4-5 zones you and fuels sustained Twin Fang trades you lose. |
| Level 6 | Cassiopeia | Petrifying Gaze at 6 face-checks and hard-counters your engage from range. |
| First item | Cassiopeia | Her first-item Twin Fang ramp DPS still scales harder than your early spike. |
| Two+ items | Ryze | Full-build Ryze finally out-bursts her before her ramping DPS takes over. |
Cassiopeia pushes first with Noxious Blast, shoving you under tower and poking as you last-hit; level 2 is even as you both trade spells without a kill threat, so soak XP and dodge her Q.
The full Ryze vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
Become a Founding Member — $1.99/month →🔒 Secure checkout · 💰 7-day money-back guarantee · ✋ Cancel anytime
Early Access price — $3.99/month for new members after launch.
Playing the other side? Cassiopeia vs Ryze guide →
All Ryze mid lane matchups →
Also played in: Top Lane