Pantheon vs Qiyana — Mid Lane Matchup Guide

How to win lane as Pantheon against Qiyana · 49.62% win rate over 266 Emerald+ games · Updated 2026-07-27

Verdict: Pantheon is favoured — Pantheon owns 5 of the 7 game windows to Qiyana's 2. Pantheon wins 49.62% of games vs Qiyana in mid lane (266 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1PantheonYour level-1 point-and-click W stun and Q poke bully a squishy melee assassin who has no waveclear or trade tools yet.
Level 2PantheonYour level-2 W-Q all-in with Mortal Will stacking is far stronger than Qiyana's empty early kit.
Level 3PantheonAt 3 you out-trade her easily since she still lacks an element combo and you can block her Q with Aegis Assault.
Levels 4-5PantheonThrough 4-5 you keep priority and out-sustain her poke while denying her the farm she needs to spike.
Level 6QiyanaAt 6 Qiyana's Edge of Ixtal shockwaves off terrain for a stun-execute, giving her the all-in in the 6-9 window.
First itemQiyanaWith an element plus her first item her combo out-bursts you from fog before your stacks matter.
Two+ itemsPantheonBy two items your Aegis Assault block and Shield Vault stun neutralize her burst and leave her with no escape.

Early game (levels 1–5)

You crush levels 1-3: your W-Q level-2 all-in is point-and-click while Qiyana is a squishy melee assassin with no element setup and no waveclear, so every time she steps up to farm you stun and stack Mortal Will for the kill. Hold Aegis Assault for her empowered Q auto and freeze just short of your tower to deny her the elements she needs to trade back.

Read the rest of this matchup

The full Pantheon vs Qiyana report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Playing the other side? Qiyana vs Pantheon guide →
All Pantheon mid lane matchups →