The champions that counter Orianna hardest in mid lane are Xerath (42.14%), Aurelion Sol (43.16%) and Syndra (44.25%) — those are Orianna's own pooled win rates. The easiest matchups are Azir (53.82%), Cassiopeia (53.41%) and Mel (51.88%).
46 researched matchup guides for Orianna in mid lane, most-played first. Win rates are Orianna's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Orianna vs Viktor | 47.75% | 8,933 | Leans Viktor |
| Orianna vs Syndra | 44.25% | 8,081 | Syndra favoured |
| Orianna vs Sylas | 47% | 6,840 | Leans Sylas |
| Orianna vs Ahri | 45.69% | 6,789 | Leans Ahri |
| Orianna vs Yasuo | 48.62% | 5,253 | Leans Yasuo |
| Orianna vs Yone | 47.13% | 4,700 | Leans Yone |
| Orianna vs Zed | 47.13% | 4,301 | Leans Zed |
| Orianna vs Xerath | 42.14% | 4,127 | Xerath favoured |
| Orianna vs Malzahar | 48.16% | 3,985 | Leans Malzahar |
| Orianna vs Lux | 46.85% | 3,893 | Leans Lux |
| Orianna vs Akali | 46.9% | 3,885 | Leans Akali |
| Orianna vs Katarina | 46.35% | 3,845 | Leans Katarina |
| Orianna vs Twisted Fate | 48.36% | 3,805 | Leans Twisted Fate |
| Orianna vs Vladimir | 47.43% | 3,635 | Leans Vladimir |
| Orianna vs Hwei | 47.61% | 3,432 | Leans Hwei |
| Orianna vs Lissandra | 47.29% | 3,405 | Leans Lissandra |
| Orianna vs Naafiri | 47.4% | 3,365 | Leans Naafiri |
| Orianna vs Karma | 50.2% | 2,745 | Even |
| Orianna vs Mel | 51.88% | 2,735 | Leans Orianna |
| Orianna vs LeBlanc | 46.66% | 2,724 | Leans LeBlanc |
| Orianna vs Fizz | 46.4% | 2,709 | Leans Fizz |
| Orianna vs Ryze | 48.42% | 2,654 | Leans Ryze |
| Orianna vs Diana | 45.71% | 2,582 | Leans Diana |
| Orianna vs Galio | 48.58% | 2,532 | Leans Galio |
| Orianna vs Veigar | 45.06% | 2,532 | Leans Veigar |
| Orianna vs Talon | 46.36% | 2,349 | Leans Talon |
| Orianna vs Irelia | 47.82% | 2,246 | Leans Irelia |
| Orianna vs Ekko | 45.62% | 2,078 | Leans Ekko |
| Orianna vs Akshan | 46.7% | 2,004 | Leans Akshan |
| Orianna vs Aurora | 46.74% | 1,932 | Leans Aurora |
| Orianna vs Zoe | 45.2% | 1,927 | Leans Zoe |
| Orianna vs Vex | 47.45% | 1,842 | Leans Vex |
| Orianna vs Ziggs | 46.02% | 1,819 | Leans Ziggs |
| Orianna vs Anivia | 46.52% | 1,608 | Leans Anivia |
| Orianna vs Qiyana | 48.69% | 1,571 | Leans Qiyana |
| Orianna vs Kassadin | 45.12% | 1,547 | Leans Kassadin |
| Orianna vs Pantheon | 50.59% | 1,510 | Even |
| Orianna vs Annie | 46.04% | 1,503 | Leans Annie |
| Orianna vs Swain | 48.1% | 1,266 | Leans Swain |
| Orianna vs Brand | 51.59% | 1,190 | Leans Orianna |
| Orianna vs Cassiopeia | 53.41% | 1,129 | Leans Orianna |
| Orianna vs Taliyah | 48.34% | 1,117 | Leans Taliyah |
| Orianna vs Aurelion Sol | 43.16% | 1,096 | Aurelion Sol favoured |
| Orianna vs Azir | 53.82% | 1,059 | Leans Orianna |
| Orianna vs Neeko | 50.98% | 767 | Leans Orianna |
| Orianna vs Locke | — | — | — |