Orianna vs Syndra — Mid Lane Matchup Guide

How to win lane as Orianna against Syndra · 45.76% win rate over 3,990 Emerald+ games · Updated 2026-07-27

Verdict: Syndra is favoured — Syndra owns 5 of the 7 game windows to Orianna's 1. Play it patient and win your windows. Orianna wins 45.76% of games vs Syndra in mid lane (3,990 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1OriannaLevel 1 favours you before Syndra has the spheres to out-range your ball.
Level 2SyndraLevel 2 flips to Syndra once her Q-E scatter-stun comes online and out-pokes you.
Level 3SyndraLevel 3 is Syndra's as her cheaper, longer-range spheres win the trade war.
Levels 4-5SyndraLevels 4-5 stay Syndra's because her stun zones you off farm with impunity.
Level 6Even / skillLevel 6 is skill — her point-and-click execute matches your setup ult only with jungle help.
First itemSyndraFirst item favours Syndra as sphere-empowered burst spikes past your shielding.
Two+ itemsSyndraAt two-plus items Syndra out-scales the poke duel and chunks you from max range.

Early game (levels 1–5)

Only level 1 is yours, before her spheres are online; land the ball early because from level 2 on she out-ranges your Command: Attack and her Q-E stun dictates the wave.

Read the rest of this matchup

The full Orianna vs Syndra report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Syndra vs Orianna guide →
All Orianna mid lane matchups →