The champions that counter Mel hardest in mid lane are Fizz (40.37%), Kassadin (43.18%) and Xerath (43.18%) — those are Mel's own pooled win rates. The easiest matchups are Swain (50.27%), Ryze (50.15%) and Neeko (49.42%).
46 researched matchup guides for Mel in mid lane, most-played first. Win rates are Mel's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Mel vs Ahri | 48.27% | 11,569 | Leans Ahri |
| Mel vs Viktor | 43.72% | 8,251 | Viktor favoured |
| Mel vs Syndra | 43.78% | 7,227 | Syndra favoured |
| Mel vs Sylas | 44.62% | 6,671 | Sylas favoured |
| Mel vs Yasuo | 47.49% | 6,545 | Leans Yasuo |
| Mel vs Yone | 47.5% | 5,589 | Leans Yone |
| Mel vs Xerath | 43.18% | 5,586 | Xerath favoured |
| Mel vs Zed | 46.16% | 5,401 | Leans Zed |
| Mel vs Malzahar | 45.45% | 4,911 | Leans Malzahar |
| Mel vs Lux | 48.6% | 4,611 | Leans Lux |
| Mel vs Twisted Fate | 47.26% | 4,484 | Leans Twisted Fate |
| Mel vs Fizz | 40.37% | 4,097 | Fizz favoured |
| Mel vs Lissandra | 45.37% | 3,967 | Leans Lissandra |
| Mel vs Hwei | 45.37% | 3,950 | Leans Hwei |
| Mel vs Katarina | 43.74% | 3,768 | Katarina favoured |
| Mel vs Vladimir | 43.22% | 3,693 | Vladimir favoured |
| Mel vs Naafiri | 47.16% | 3,609 | Leans Naafiri |
| Mel vs Akali | 46.12% | 3,005 | Leans Akali |
| Mel vs LeBlanc | 47.61% | 2,865 | Leans LeBlanc |
| Mel vs Orianna | 48.12% | 2,735 | Leans Orianna |
| Mel vs Zoe | 45.92% | 2,731 | Leans Zoe |
| Mel vs Diana | 43.62% | 2,719 | Diana favoured |
| Mel vs Talon | 45.89% | 2,687 | Leans Talon |
| Mel vs Karma | 47.25% | 2,612 | Leans Karma |
| Mel vs Veigar | 45.51% | 2,595 | Leans Veigar |
| Mel vs Ryze | 50.15% | 2,387 | Even |
| Mel vs Irelia | 44.63% | 2,288 | Irelia favoured |
| Mel vs Vex | 49.21% | 2,280 | Leans Vex |
| Mel vs Galio | 43.92% | 2,256 | Galio favoured |
| Mel vs Ekko | 45% | 2,178 | Ekko favoured |
| Mel vs Akshan | 44.22% | 2,105 | Akshan favoured |
| Mel vs Qiyana | 48.74% | 1,904 | Leans Qiyana |
| Mel vs Ziggs | 43.85% | 1,886 | Ziggs favoured |
| Mel vs Anivia | 45.61% | 1,846 | Leans Anivia |
| Mel vs Kassadin | 43.18% | 1,781 | Kassadin favoured |
| Mel vs Aurora | 47.36% | 1,630 | Leans Aurora |
| Mel vs Pantheon | 45.72% | 1,601 | Leans Pantheon |
| Mel vs Brand | 46.66% | 1,528 | Leans Brand |
| Mel vs Annie | 44.75% | 1,439 | Annie favoured |
| Mel vs Swain | 50.27% | 1,325 | Even |
| Mel vs Taliyah | 46.48% | 1,179 | Leans Taliyah |
| Mel vs Aurelion Sol | 44.14% | 1,151 | Aurelion Sol favoured |
| Mel vs Cassiopeia | 49.15% | 879 | Leans Cassiopeia |
| Mel vs Neeko | 49.42% | 785 | Even |
| Mel vs Azir | 47.42% | 757 | Leans Azir |
| Mel vs Locke | — | — | — |