Cassiopeia vs Yone — Mid Lane Matchup Guide

How to win lane as Cassiopeia against Yone · 51.65% win rate (2,329 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: Cassiopeia is slightly favoured — 51.65% win rate over 2,329 games, and Cassiopeia's game plan below claims 4 of the 7 stage windows.

At a glance

He wants to run you down — grounded fighters don't run anywhere, and petrified ones don't fight.

Track: Yone's E — Soul Unbound (22–10s cooldown). His burst window — survive it and punish the body he snaps back to.

Do

  • Kite backward with Q's movement-speed slow
  • Ground his dash bridge mid-engage
  • Hold R face-on for the all-in

Don't

  • Burn W on poke spacing
  • Fight inside his wave at even HP
  • Pop R on a feint before the real commit

Runes & build vs Yone

Start
Doran's Ring + 2 Health Potions
First back
Tear of the Goddess + Dark Seal (≈800g)
First item
Seraph's Embrace
Then
Liandry's Torment
Boots
No boots — passive grants scaling move speed (extra item slot)
Runes
Conqueror (Precision): Presence of Mind, Legend: Haste, Last Stand · Sorcery: Manaflow Band, Transcendence · Shards: Adaptive Force, Adaptive Force, Health

Favour timeline — the windows in Cassiopeia's game plan

Read from Cassiopeia's seat: which stage windows this plan plays for against Yone.

StageFavouredWhy
Level 1Even / skillLevel 1 trades are close since neither champion has a hard engage tool yet, so it comes down to who plays minion positioning better.
Level 2Even / skillLevel 2 stays even because his Q3 knockup is still on a long cooldown loop and your kit isn't fully online, so poke exchanges roughly cancel out.
Level 3CassiopeiaAt level 3 your full combo (Q-W-E) outpaces anything he can answer with while dashing through minions, so you start winning trades outright.
Levels 4-5CassiopeiaLevels 4-5 extend that lead as your DoT uptime and Miasma zoning make his approach paths actively dangerous for him.
Level 6CassiopeiaLevel 6 is your biggest spike — Petrifying Gaze punishes any all-in commitment he makes, so you dominate any fight he starts.
First itemCassiopeiaWith your first item online your DoT and slow output make it nearly impossible for him to stick on you, keeping the lane firmly in your favor.
Two+ itemsYoneLate-game 2+ item teamfights favor him because his ultimate is a flanking tool that lets a fed Yone bypass the frontline and burst you down before you can react.

How to beat Yone as Cassiopeia: the early game

Levels 1-2 are close to even — his third Mortal Steel knocks up, but he cannot commit without wave support, and your ranged poke keeps him from walking up freely. By level 3 you have Noxious Blast and Twin Fang, and the moment he steps through minions to stack Mortal Steel you are already chunking him from 850, forcing him to eat poke or delay the combo. Spirit Cleave shields him every 14 seconds, so make him spend it on the wave.

Hardest and easiest matchups for Cassiopeia in mid lane

Pooled Emerald+ win rates from Cassiopeia's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Cassiopeia vs Yone report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Cassiopeia vs Yone in mid lane?

Cassiopeia, slightly — a 51.65% win rate edge over 2,329 games; execution can flip it.

Is Cassiopeia vs Yone a skill matchup?

Mostly — Cassiopeia has a small statistical edge (51.65% win rate), but execution decides this lane far more than the pick does.

Does Cassiopeia counter Yone?

Not a hard counter — Cassiopeia has a slight edge (51.65% win rate), and play quality decides the rest.

What runes does Cassiopeia take vs Yone?

Cassiopeia takes Conqueror on the Precision tree with Presence of Mind, Legend: Haste and Last Stand, and Sorcery secondary (Manaflow Band and Transcendence) vs Yone.

What should Cassiopeia build vs Yone?

Start Doran's Ring + 2 Health Potions and back for Tear of the Goddess + Dark Seal (≈800g). Build Seraph's Embrace first, then Liandry's Torment, with No boots — passive grants scaling move speed (extra item slot).

Related guides

Playing the other side? Yone vs Cassiopeia guide →
All Cassiopeia mid lane matchups →

More Cassiopeia mid lane matchups: vs Vladimir · vs Xerath · vs Yasuo · vs Zed · vs Ziggs · vs Zoe

Also played in: Top Lane