Kog'Maw vs Vayne — Bot Lane (ADC) Matchup Guide

How to win lane as Kog'Maw against Vayne · 53.35% win rate over 1,209 Emerald+ games · Updated 2026-07-27

Verdict: Winnable despite the lane — Vayne owns 1 of the 7 game windows, yet the win rate favours Kog'Maw: survive their windows and the game is yours. Kog'Maw wins 53.35% of games vs Vayne in bot lane (adc) (1,209 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillLevel 1 is even because both of you just last-hit and neither auto range meaningfully bullies the other yet.
Level 2Even / skillLevel 2 stays a skill check as her Tumble trade and your empowered W poke roughly cancel out.
Level 3Even / skillLevel 3 is even because Q's attack-speed steroid answers her Silver Bolts DPS at max spacing.
Levels 4-5Even / skillLevels 4-5 remain skill-dependent on whether you kite her Tumbles or she catches a Condemn wall.
Level 6Even / skillAt Level 6 Vayne is ahead: Final Hour plus invisible Condemn all-ins beat your slow Living Artillery reload.
First itemVayneAt first item it re-evens as your W range and crit spike restore parity in the duel.
Two+ itemsEven / skillWith 2+ items it returns to a skill check because her Final Hour uptime offsets your scaling if she gets on you.

Early game (levels 1–5)

Levels 1-2 are a genuine coin-flip: her Tumble auto trades hurt but you out-range her the instant W is up, so poke with empowered autos and farm safely rather than committing.

Read the rest of this matchup

The full Kog'Maw vs Vayne report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Vayne vs Kog'Maw guide →
All Kog'Maw bot lane (adc) matchups →