Karma vs Dr. Mundo — Top Lane Matchup Guide

How to win lane as Karma against Dr. Mundo · 50% win rate over 30 Emerald+ games · Updated 2026-07-27

Verdict: Dr. Mundo is favoured — Dr. Mundo owns 3 of the 7 game windows to Karma's 1. Play it patient and win your windows. Karma wins 50% of games vs Dr. Mundo in top lane (30 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1KarmaMantra is up from level 1, so my RQ Soulflare zone chips him before his passive regen or Q heal exists to answer it.
Level 2Even / skillAt level 2 his cleaver can't yet out-pressure my single Q, but my thin frame can't punish either — it's even and mana-dependent for both of us.
Level 3Dr. MundoInfected Cleaver and his passive are online now, so he heals on every cleaver and last-hits safely from range through my poke.
Levels 4-5Dr. MundoThrough 4-5 his percent-HP cleaver heals out-sustain my Q/RQ rotations — I can't tax a target literally built to out-heal chip.
Level 6Even / skillMaximum Dosage heals him but can't lock me down, and my range plus Inspire's speed keep me safe — neither of us kills the other at 6.
First itemDr. MundoHis first drain-tank item makes the cleaver hurt and the heal stick, outvaluing my first AP spike in a straight lane trade.
Two+ itemsEven / skillHe scales to unkillable, but I out-poke his pushes and out-roam him — if I cashed my lead early the late game stays even.

Early game (levels 1–5)

Level 1 is genuinely mine — Mantra is up instantly, so I open with RQ Soulflare and drop the delayed zone on him as he steps up to last-hit, and his level-1 passive regen is far too small to erase that chunk. Stack a normal Inner Flame on top and he's pushed off CS with no heal to answer yet. But the moment Infected Cleaver and his passive are online, the trade math flips: he last-hits from cleaver range, heals my single-Q chip back on every hit, and there's nothing to all-in into — my W tether and thin frame can't burst a Mundo who just regens it. Don't waste mana trying to tax a target who out-sustains it.

Read the rest of this matchup

The full Karma vs Dr. Mundo report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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