Dr. Mundo vs Karma — Top Lane Matchup Guide

How to win lane as Dr. Mundo against Karma · 52.36% win rate over 2,859 Emerald+ games · Updated 2026-07-27

Verdict: Dr. Mundo is favoured — Dr. Mundo owns 3 of the 7 game windows to Karma's 1. Dr. Mundo wins 52.36% of games vs Karma in top lane (2,859 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1KarmaKarma's level 1 Q Inner Flame poke outranges your kit before Infected Bonesaw is online.
Level 2Even / skillAt level 2 it's a skill trade — her poke versus your farm, neither clearly ahead.
Level 3Dr. MundoLevel 3 Q Infected Bonesaw lets you shove and out-sustain her mantra-gated poke.
Levels 4-5Dr. MundoThrough 4-5 your regen answers her poke while her cooldowns keep it skill-based edges to you.
Level 6Even / skillAt 6 it's even-ish: you gain R but her shields and disengage blunt your all-in.
First itemDr. MundoItem-one grievous plus HP lets you walk through her shields and cleaver her down.
Two+ itemsEven / skillTwo items in it's skill-dependent — you're unkillable but her utility still swings fights.

Early game (levels 1–5)

Karma edges level 1 with Q Inner Flame range, but by level 2 it's roughly even skill — she can poke but her mana and mantra cooldown limit how often, so respect the Mantra-Q burst and otherwise farm calmly without eating free harass.

Read the rest of this matchup

The full Dr. Mundo vs Karma report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Karma vs Dr. Mundo guide →
All Dr. Mundo top lane matchups →