How to win lane as Seraphine against Karma · 51.84% win rate (23,161 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
A song mirror your echo tilts — every third spell doubles what their kit singles.
Track: Karma's W — Focused Resolve (12s cooldown). The root tether — break it with range or line of sight.
Read from Seraphine's seat: which stage windows this plan plays for against Karma.
This is Seraphine's own plan; across 23,161 pooled games the lane is leaning Seraphine.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Karma | Karma-favoured at 1 because her Mantra-Q burst out-pokes your early casts. |
| Level 2 | Karma | Karma-favoured at 2 as her Q+W root trade beats your two-cast spike. |
| Level 3 | Karma | Karma-favoured at 3 with continued Mantra poke keeping you off farm. |
| Levels 4-5 | Karma | Karma-favoured at 4-5 since her root setup and poke keep pressuring your ADC. |
| Level 6 | Even / skill | Even at 6 once your Encore matches her long-standing Mantra tempo. |
| First item | Even / skill | Even at first item as your poke and sustain trade evenly with her Mantra-Q. |
| Two+ items | Seraphine | Seraphine-favoured at 2+ items where Encore AoE charm outscales her utility ult. |
Levels 1-4 belong to Karma: her Mantra-empowered Q poke and W root out-trade your Q+E, so play safe, keep your shield for her all-in, and give up a little farm rather than eat her burst. Her empowered rotation reaches past yours, so trade only in the gaps her cooldowns leave. Keep the note count building off the wave, shield your carry preemptively, and hold the root for the moment the empowered cast has already been spent on someone else.
Pooled Emerald+ win rates from Seraphine's side, sampled July 2026.
The full Seraphine vs Karma report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Seraphine, slightly — a 51.84% win rate edge over 23,161 games; execution can flip it.
Mostly — Seraphine has a small statistical edge (51.84% win rate), but execution decides this lane far more than the pick does.
Not a hard counter — Seraphine has a slight edge (51.84% win rate), and play quality decides the rest.
Seraphine takes Summon Aery on the Sorcery tree with Manaflow Band, Transcendence and Scorch, and Inspiration secondary (Biscuit Delivery and Cosmic Insight) vs Karma.
Start World Atlas + potions and back for Oblivion Orb piece vs sustain. Build Moonstone / Helia first, then Redemption / Mikael's, with Mercury's / Swiftness.
Playing the other side? Karma vs Seraphine guide →
All Seraphine support matchups →
More Seraphine support matchups: vs Galio · vs Hwei · vs Janna · vs Leona · vs Lulu · vs Lux