The champions that counter Sylas hardest in mid lane are Vex (45.53%), Taliyah (47.69%) and Galio (48.37%) — those are Sylas's own pooled win rates. The easiest matchups are Mel (55.38%), Azir (54.89%) and Zed (53.14%).
46 researched matchup guides for Sylas in mid lane, most-played first. Win rates are Sylas's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Sylas vs Ahri | 50.99% | 26,206 | Leans Sylas |
| Sylas vs Viktor | 50.82% | 20,286 | Leans Sylas |
| Sylas vs Zed | 53.14% | 17,863 | Leans Sylas |
| Sylas vs Yasuo | 49.34% | 16,679 | Even |
| Sylas vs Akali | 50.42% | 15,810 | Even |
| Sylas vs Yone | 50.99% | 15,399 | Leans Sylas |
| Sylas vs Syndra | 50.94% | 15,176 | Leans Sylas |
| Sylas vs Katarina | 49.95% | 13,716 | Even |
| Sylas vs Twisted Fate | 51.57% | 13,709 | Leans Sylas |
| Sylas vs Lissandra | 51.14% | 11,737 | Leans Sylas |
| Sylas vs Fizz | 52.33% | 11,176 | Leans Sylas |
| Sylas vs Malzahar | 49.18% | 10,821 | Leans Malzahar |
| Sylas vs Galio | 48.37% | 10,523 | Leans Galio |
| Sylas vs Lux | 51.35% | 10,518 | Leans Sylas |
| Sylas vs Diana | 50.29% | 10,200 | Even |
| Sylas vs Naafiri | 48.54% | 10,192 | Leans Naafiri |
| Sylas vs Vladimir | 49.22% | 9,334 | Leans Vladimir |
| Sylas vs Hwei | 48.89% | 9,034 | Leans Hwei |
| Sylas vs LeBlanc | 51.9% | 8,686 | Leans Sylas |
| Sylas vs Xerath | 51.47% | 8,451 | Leans Sylas |
| Sylas vs Ekko | 51.88% | 8,257 | Leans Sylas |
| Sylas vs Ryze | 50.49% | 8,179 | Even |
| Sylas vs Karma | 52.8% | 7,678 | Leans Sylas |
| Sylas vs Vex | 45.53% | 7,539 | Leans Vex |
| Sylas vs Talon | 51.65% | 7,324 | Leans Sylas |
| Sylas vs Irelia | 52.67% | 6,876 | Leans Sylas |
| Sylas vs Orianna | 53% | 6,840 | Leans Sylas |
| Sylas vs Mel | 55.38% | 6,671 | Sylas favoured |
| Sylas vs Veigar | 50.33% | 6,086 | Even |
| Sylas vs Kassadin | 50.81% | 5,515 | Leans Sylas |
| Sylas vs Zoe | 49.83% | 5,429 | Even |
| Sylas vs Aurora | 50.02% | 5,360 | Even |
| Sylas vs Qiyana | 52.34% | 5,338 | Leans Sylas |
| Sylas vs Ziggs | 51.91% | 5,251 | Leans Sylas |
| Sylas vs Akshan | 51.07% | 5,112 | Leans Sylas |
| Sylas vs Swain | 53.07% | 4,692 | Leans Sylas |
| Sylas vs Anivia | 50.23% | 4,623 | Even |
| Sylas vs Pantheon | 50% | 4,620 | Even |
| Sylas vs Cassiopeia | 49.53% | 3,896 | Even |
| Sylas vs Brand | 50.75% | 3,669 | Leans Sylas |
| Sylas vs Taliyah | 47.69% | 3,598 | Leans Taliyah |
| Sylas vs Annie | 50.21% | 3,469 | Even |
| Sylas vs Azir | 54.89% | 2,760 | Leans Sylas |
| Sylas vs Aurelion Sol | 52.03% | 2,606 | Leans Sylas |
| Sylas vs Neeko | 52.65% | 2,564 | Leans Sylas |
| Sylas vs Locke | — | — | — |