Locke vs Karma — Mid Lane Matchup Guide

How to win lane as Locke against Karma · 50% win rate · Updated 2026-07-27

Verdict: Locke is favoured — Locke owns 7 of the 7 game windows. Locke wins 50% of games vs Karma in mid lane.

Favour timeline — who owns each window

StageFavouredWhy
Level 1LockeYou win level 1 since Karma lacks any early all-in or trade threat.
Level 2LockeLevel 2 stays yours as your damage outpaces her poke.
Level 3LockeLevel 3 favours you with real trade patterns she can't match.
Levels 4-5LockeLevels 4-5 you dominate all-in windows she can't answer.
Level 6LockeAt 6 your ult gives kill pressure while her R only shields.
First itemLockeFirst item you burst through her mantra shield.
Two+ itemsLockeLate you keep solo-kill priority once her RE is baited out.

Early game (levels 1–5)

Karma has no early kill pressure and you can walk her down at levels 1-2, only respecting the QE snare which is her one tool to create distance.

Read the rest of this matchup

The full Locke vs Karma report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Karma vs Locke guide →
All Locke mid lane matchups →

Also played in: Top Lane