How to win lane as Senna against Varus · 55.99% win rate over 3,406 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Varus | Level 1 Varus's charged Q outranges your Q and pokes you off CS. |
| Level 2 | Varus | Level 2 his W-E combo chips your sustain and keeps the range lead. |
| Level 3 | Varus | Level 3 his Blight-stacked Q burst out-trades you in any exchange. |
| Levels 4-5 | Varus | Levels 4-5 his poke keeps you pinned behind the wave. |
| Level 6 | Varus | Level 6 Chain of Corruption lets him and his support collapse for a kill. |
| First item | Varus | At first item his W-Q burst peaks and can two-tap you through minions. |
| Two+ items | Senna | With two-plus items your range and kiting flip the immobile Varus to your favour. |
Levels 1-2 Varus has the range edge: his charged Q outreaches your Q and his W-E combo chips your sustain, so respect the poke, dodge his arrows and only farm when his abilities are down.
The full Senna vs Varus report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Varus vs Senna guide →
All Senna bot lane (adc) matchups →