Senna vs Miss Fortune — Bot Lane (ADC) Matchup Guide

How to win lane as Senna against Miss Fortune · 55.27% win rate over 7,827 Emerald+ games · Updated 2026-07-27

Verdict: Senna is favoured — Senna owns 5 of the 7 game windows to Miss Fortune's 2. Senna wins 55.27% of games vs Miss Fortune in bot lane (adc) (7,827 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1SennaSenna out-ranges Miss Fortune at level 1 and controls the first trade.
Level 2SennaLevel 2 Q poke keeps Senna ahead of MF's early Love Tap pattern.
Level 3SennaAt 3 Senna's range lead lets her chip MF before her ult spike.
Levels 4-5SennaThrough 4-5 Senna still leads while MF lacks her lane-winning tool.
Level 6Miss FortuneAt 6 Miss Fortune's Bullet Time flips the lane into her kill window.
First itemMiss FortuneFirst item plus Strut tempo makes MF the stronger 2v2 all-in threat.
Two+ itemsSennaBy 2+ items Senna's range and global utility beat MF's interruptible channel.

Early game (levels 1–5)

You own levels 1-2; Senna's superior range and Q poke beat Miss Fortune's early auto game, so control the wave and chip her before her damage spikes come online.

Read the rest of this matchup

The full Senna vs Miss Fortune report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Playing the other side? Miss Fortune vs Senna guide →
All Senna bot lane (adc) matchups →