Miss Fortune vs Seraphine — Bot Lane (ADC) Matchup Guide

How to win lane as Miss Fortune against Seraphine · 51.39% win rate over 9,889 Emerald+ games · Updated 2026-07-27

Verdict: Miss Fortune is favoured — Miss Fortune owns 5 of the 7 game windows to Seraphine's 1. Miss Fortune wins 51.39% of games vs Seraphine in bot lane (adc) (9,889 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Miss FortuneLevel 1 your base damage beats a poke-reliant, immobile Seraphine.
Level 2Miss FortuneLevel 2 you out-trade her autos and can dodge her early skillshots.
Level 3Miss FortuneLevel 3 you out-DPS her and shove her low on mana under tower.
Levels 4-5Even / skillLevels 4-5 it evens out as her Q poke and E root can punish missteps.
Level 6Miss FortuneLevel 6 Bullet Time out-damages her all-in with no escape for her.
First itemMiss FortuneYour first-item spike lets you dive her immobile kit before her poke adds up.
Two+ itemsSeraphineAt 2+ items her shields, poke, and chain-charm ult out-scale you in fights.

Early game (levels 1–5)

Levels 1-2 you have stronger base damage than a poke-reliant Seraphine and she has no mobility, so trade autos when she steps up and use E to slow her so her skillshots are easier to walk out of.

Read the rest of this matchup

The full Miss Fortune vs Seraphine report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

Become a Founding Member — $1.99/month →

🔒 Secure checkout · 💰 7-day money-back guarantee · ✋ Cancel anytime
Early Access price — $3.99/month for new members after launch.

Related guides

Playing the other side? Seraphine vs Miss Fortune guide →
All Miss Fortune bot lane (adc) matchups →