How to win lane as Zac against Cassiopeia · 56.92% win rate over 65 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Cassiopeia | Cassiopeia's Q-E poison poke wins the level-1 exchange. |
| Level 2 | Cassiopeia | At 2 her ramping E damage keeps you off the wave. |
| Level 3 | Cassiopeia | Level 3 grounded W plus poison lets her control your approach. |
| Levels 4-5 | Cassiopeia | Through 4-5 her sustained DPS out-damages your HP regen. |
| Level 6 | Cassiopeia | Her level-6 R cancels your engage and keeps her ahead. |
| First item | Cassiopeia | At first item her poison DPS melts you before you reach her. |
| Two+ items | Zac | With 2+ items your tank pool eats her poison and E-R kills her. |
Cassiopeia pokes you off the wave with Q and E poison and grounds your approach with W, so walking up to charge Unstable Matter just feeds her ramping E — soak XP at range and don't slingshot into her poison.
The full Zac vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Cassiopeia vs Zac guide →
All Zac top lane matchups →