Sett vs Karma — Top Lane Matchup Guide

How to win lane as Sett against Karma · 52.26% win rate over 3,643 Emerald+ games · Updated 2026-07-27

Verdict: Sett is favoured — Sett owns 3 of the 7 game windows to Karma's 1. Sett wins 52.26% of games vs Karma in top lane (3,643 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1KarmaKarma's L1 Mantra-Q Renewal out-ranges and pokes Sett before he can close.
Level 2Even / skillLevel 2 is even once Sett has Q to trade back into her Mantra burst.
Level 3SettSett takes L3 committing with E and Haymaker whenever her Q root is down.
Levels 4-5SettSett stays ahead L4-5 forcing Karma to burn Mantra shields defensively.
Level 6Even / skillLevel 6 is even — Karma has no true ult and her E shield can absorb Sett's all-in.
First itemSettSett's first item gives the grit and true damage to kill through a shield.
Two+ itemsEven / skillLate stays even as Karma's shields and root peel offset Sett's R threat.

Early game (levels 1–5)

Level 1 is Karma's — Mantra-empowered Q Renewal out-ranges and out-pokes you before you have a gap-closer, so soak minions and don't force. Level 2 evens out once you have Q to trade back, but respect her Mantra burst.

Read the rest of this matchup

The full Sett vs Karma report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Karma vs Sett guide →
All Sett top lane matchups →