The champions that counter Twitch hardest in bot lane are Nilah (43.56%), Samira (48.05%) and Tristana (48.39%) — those are Twitch's own pooled win rates. The easiest matchups are Varus (55.23%), Heimerdinger (54.97%) and Sivir (54.86%).
29 researched matchup guides for Twitch in bot lane, most-played first. Win rates are Twitch's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Twitch vs Caitlyn | 52.1% | 21,733 | Leans Twitch |
| Twitch vs Jhin | 52.58% | 20,573 | Leans Twitch |
| Twitch vs Kai'Sa | 49.7% | 18,894 | Even |
| Twitch vs Jinx | 52.31% | 18,466 | Leans Twitch |
| Twitch vs Ezreal | 53.38% | 16,199 | Leans Twitch |
| Twitch vs Ashe | 51.72% | 13,261 | Leans Twitch |
| Twitch vs Tristana | 48.39% | 11,191 | Leans Tristana |
| Twitch vs Lucian | 50.85% | 10,725 | Leans Twitch |
| Twitch vs Senna | 49.38% | 10,641 | Even |
| Twitch vs Miss Fortune | 52.1% | 10,037 | Leans Twitch |
| Twitch vs Seraphine | 50.62% | 9,971 | Even |
| Twitch vs Vayne | 51.38% | 8,448 | Leans Twitch |
| Twitch vs Smolder | 53.03% | 8,227 | Leans Twitch |
| Twitch vs Samira | 48.05% | 7,082 | Leans Samira |
| Twitch vs Aphelios | 53.78% | 7,075 | Leans Twitch |
| Twitch vs Draven | 50.1% | 6,699 | Even |
| Twitch vs Sivir | 54.86% | 5,643 | Leans Twitch |
| Twitch vs Zeri | 51.15% | 5,251 | Leans Twitch |
| Twitch vs Ziggs | 52.95% | 4,644 | Leans Twitch |
| Twitch vs Xayah | 50.9% | 4,593 | Leans Twitch |
| Twitch vs Varus | 55.23% | 3,902 | Twitch favoured |
| Twitch vs Veigar | 51.53% | 3,198 | Leans Twitch |
| Twitch vs Nilah | 43.56% | 3,083 | Nilah favoured |
| Twitch vs Kog'Maw | 48.71% | 2,642 | Leans Kog'Maw |
| Twitch vs Kalista | 50.04% | 2,600 | Even |
| Twitch vs Swain | 52.04% | 2,600 | Leans Twitch |
| Twitch vs Corki | 50.23% | 1,726 | Even |
| Twitch vs Karthus | 49.82% | 1,393 | Even |
| Twitch vs Heimerdinger | 54.97% | 995 | Leans Twitch |